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What Is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in all living cells and central to cellular energy metabolism. It is a widely used tool compound in metabolic, redox, and longevity research. This guide summarizes its properties and laboratory handling, provided strictly for research use only (RUO).

Research Background

In published research, NAD+ functions as an essential cofactor in redox reactions and as a substrate for enzymes such as sirtuins and PARPs. It is studied in cellular-energy, mitochondrial, and aging-model contexts. NAD+ is not a drug or supplement as supplied here and is not intended for human or veterinary use.

Technical Data

Compound NAD+ (Nicotinamide Adenine Dinucleotide)
CAS Number 53-84-9
Molecular Formula C21H27N7O14P2
Molecular Weight ≈ 663.43 g/mol
Class Redox coenzyme / dinucleotide
Form Lyophilized powder
Purity 99%+ (HPLC verified)

Handling, Storage & Reconstitution (Lab Use)

Lyophilized NAD+ is typically stored at −20 °C, protected from light and moisture. Laboratory reconstitution commonly uses sterile or bacteriostatic water; reconstituted material is generally refrigerated and used promptly, as NAD+ can degrade in solution. Follow your institution’s handling and biosafety procedures.

Frequently Asked Questions

What is NAD+?

NAD+ is a redox coenzyme central to cellular energy metabolism, studied in metabolic and longevity research. It is supplied for laboratory research only.

What enzymes use NAD+?

Research literature describes NAD+ as a substrate/cofactor for sirtuins, PARPs, and numerous redox enzymes.

Buy NAD+ for Research

Zama Biosciences supplies NAD+ in multiple sizes, independently tested. See related longevity-research compound Epithalon.

Research Use Only. Not drugs, supplements, or medical devices; not for human or veterinary use, consumption, or diagnostic application. Not evaluated by the FDA.

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