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What Is Epithalon (Epitalon)?

Epithalon (also spelled Epitalon) is a synthetic tetrapeptide — Ala-Glu-Asp-Gly (AEDG) — based on the natural pineal peptide epithalamin. It is a prominent tool compound in longevity and telomere research. This guide summarizes its structure, research background, and laboratory handling, provided strictly for research use only (RUO).

Research Background

In published preclinical and in-vitro research, Epithalon has been studied in the context of telomerase activity, telomere biology, pineal/circadian signaling, and cellular-aging models. It is not a drug or supplement and is not intended for human or veterinary use.

Technical Data

Compound Epithalon (Epitalon)
CAS Number 307297-39-8
Molecular Formula C14H22N4O9
Molecular Weight ≈ 390.35 g/mol
Sequence Ala-Glu-Asp-Gly (AEDG)
Form Lyophilized powder
Purity 99%+ (HPLC / LC-MS verified)

Handling, Storage & Reconstitution (Lab Use)

Lyophilized Epithalon is typically stored at −20 °C, protected from light. Laboratory reconstitution commonly uses bacteriostatic or sterile water; reconstituted peptide is generally refrigerated and used within a limited window. Follow your institution’s handling and biosafety procedures.

Frequently Asked Questions

What is Epithalon?

Epithalon is a synthetic AEDG tetrapeptide studied in preclinical telomere, pineal, and cellular-aging research. It is for laboratory research only.

Is Epithalon the same as Epitalon?

Yes — “Epithalon” and “Epitalon” are alternate spellings of the same AEDG tetrapeptide.

Buy Epithalon for Research

Zama Biosciences supplies Epithalon, independently HPLC/LC-MS tested. See related longevity-research compound NAD+.

Research Use Only. Not drugs, supplements, or medical devices; not for human or veterinary use, consumption, or diagnostic application. Not evaluated by the FDA.

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