Melanotan II (MT-2): Research Guide & Technical Data

What Is Melanotan II (MT-2)?

Melanotan II (MT-2) is a synthetic cyclic peptide analog of α-melanocyte-stimulating hormone (α-MSH) and a melanocortin receptor agonist. It is a widely referenced compound in melanocortin and pigmentation research. This guide summarizes its structure, mechanism, and laboratory handling, provided strictly for research use only (RUO).

Mechanism of Action

Melanotan II is a non-selective agonist across melanocortin receptors, with research interest in MC1R (pigmentation pathways) and MC4R (central melanocortin signaling). It is not a drug or supplement and is not intended for human or veterinary use.

Technical Data

Compound	Melanotan II (MT-2)
CAS Number	121062-08-6
Molecular Formula	C50H69N15O9
Molecular Weight	≈ 1024.2 g/mol
Target	Melanocortin receptor agonist (MC1R / MC4R)
Form	Lyophilized powder
Purity	99%+ (HPLC / LC-MS verified)

Handling, Storage & Reconstitution (Lab Use)

Lyophilized Melanotan II is typically stored at −20 °C, protected from light. Laboratory reconstitution commonly uses bacteriostatic or sterile water; reconstituted peptide is generally refrigerated and used within a limited window. Follow your institution’s handling and biosafety procedures.

Frequently Asked Questions

What is Melanotan II?

Melanotan II (MT-2) is a synthetic melanocortin receptor agonist studied in preclinical melanocortin and pigmentation research. It is for laboratory research only.

What is the difference between Melanotan I and Melanotan II?

Melanotan I (MT-1) is more selective for the MC1R pathway, while Melanotan II (MT-2) is a broader melanocortin-receptor agonist.

Buy Melanotan II for Research

Zama Biosciences supplies Melanotan II (MT-2) 10mg, independently HPLC/LC-MS tested. See also Melanotan I (MT-1) and PT-141.

Research Use Only. Not drugs, supplements, or medical devices; not for human or veterinary use, consumption, or diagnostic application. Not evaluated by the FDA.